Developmental and Cancer Epigenetics
Wellcome to the web pages of Irina Stancheva Lab
We study how DNA methylation and silencing histone modifications contribute to regulation of gene
expression in mammalian cells. In particular, we investigate the molecular mechanisms that guide the
establishment and maintenance of DNA methylation patterns during development and cellular transformation
into cancer. We also study the crosstalk between DNA methylation and histone modifications during the
establishment and propagation of silenced chromatin states.
The lab is part of the Wellcome Trust Centre of Cell Biology at the University of Edinburgh.
Our research is funded by:
