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Developmental Epigenetics

 Wellcome to the web pages of Stancheva Lab



We study how DNA methylation and silencing histone modifications contribute to regulation of gene
expression in mammalian cells. In particular, we investigate the molecular mechanisms that guide the
establishment and maintenance of DNA methylation patterns during development and cellular transformation
into cancer. We also study the crosstalk between DNA methylation and histone modifications during the
establishment and propagation of silenced chromatin states.


The lab is part of the Institute of Cell Biology at the School of Biological Sceineces, University of Edinburgh.  
Our research is funded by: